Web Servers

The researchers of the Structural Bioinformatics Unit have developed several web server applications that are currently hosted by other servers at of the University of Balearic Islands (Spain), University of Bologna (Italy) and Centro de Investigacion Principe Felipe (Spain). In the next months a mirror of this applications will be made available on this server. Currenty you can reach these web servers using the following link.

Folding and Stability

I-Mutant1.0	Neural Network based method to predict the sign of free energy change of proteins upon single point mutation.
I-Mutant2.0	Support Vector Machine based method to predict the sign and the value of free energy change of proteins upon single point mutation.
K-Fold	Support Vector Machine based method to predict the mechanism and rate of protein folding kinetic.

Mutation and Disease

PhD-SNP	Support Vector Machine based method to discriminate between neutral or disease-related single point protein mutations.
WS-SNPs&GO	Support Vector Machine method for the detection of disease-related SNPs based on functional information
DrCancer	Support Vector Machine based method to predict cancer-causing mutations (Beta version).

Structure Comparison

ProtDeform	Method for protein structure alignment.
MatTops	Comparison of protein domains using TOPS.
SARA	Method for RNA structure alignment and RNA functional assignment.